Dr. Robert Roberts Award for Research Excellence
University of Ottawa Heart Institute
Principal Investigator · Director, BEaTS Research
Regenerative-medicine scientist uncovering how methylglyoxal damages the heart and blood vessels, and building biomaterials that help the heart repair itself.

Recognition
Repeated recognition for research excellence at the Heart Institute, and for service to Canada's research funding system.
University of Ottawa Heart Institute
Canadian Institutes of Health Research
University of Ottawa Heart Institute
Research excellence
Materials are designed, then tested in clinically relevant models of heart attack, diabetes and limb ischemia, with imaging and functional studies done in-house.
Showed that methylglyoxal impairs vascular repair and drives heart failure after a heart attack, even without diabetes, making it a new therapeutic target.
A collagen hydrogel acts as a sponge for methylglyoxal in the injured heart, a new biomaterial mechanism based on chemical scavenging, not mechanical support alone.
The first study to implicate methylglyoxal in heart-brain effects after a heart attack, with sex- and region-specific differences, opening a new research direction.
Injectable collagen hydrogels that improve blood-vessel growth and preserve heart function, evolving into a recombinant human collagen therapy.
Self-assembling peptide hydrogels repair skin, cornea and heart without toxic crosslinkers. He leads their cellular and in vivo evaluation.
Patents cover hydrogel compositions, light-activated peptide precursors and anti-methylglyoxal peptides. The collagen therapy is animal-free by design, ready for future regulatory review.
Track record
17 grants as principal or co-principal investigator.
At the Heart Institute and across Canada's funding agencies.
78 trainees across 20 years of independent research.
Alumni include faculty at Masaryk University and Soochow University, and a researcher at the National University of Córdoba.
Community engagement
Research featured on CBC's Ottawa Morning, CTV News Channel, the Globe and Mail, Maclean's, New Scientist and Heart & Stroke's On the Pulse.
Presenter at the Pint of Science Festival and the Ottawa Heart Support Group seminar series, and speaker at CIHR's 2018 CHRP funding announcement.
Co-author of two articles for young readers in Frontiers for Young Minds.
CIHR College of Reviewers since 2017, with panels in cardiovascular science, biomedical engineering and the New Frontiers in Research Fund.
Co-developed the open-source BEaTS-α and BEaTS-β bioreactors and a low-cost nanoparticle synthesis system that other labs can rebuild.
Editor of a textbook on biomaterials for cardiac regeneration and author of the cell therapy chapters in Sabiston and Spencer Surgery of the Chest.
Co-Chair in 2018 and Chair in 2019 of the city's annual meeting for cardiovascular researchers.
Selected publications
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